Independent list · re-checked September 28, 2026 · published by Primortul LLC

Antidote 71

Antidote 71 is a marketing agency at 600 4th Street in Sioux City with a second office in Omaha. It organises its work into attract, engage, convert and grow stages that cover SEO, SEM, paid social, retargeting, geofencing, email, marketing automation and CRM management alongside branding and video. It works mainly with medical, financial, construction and manufacturing companies. Nobody pays to be ranked.

Why it’s hereListed by Expertise.com among Sioux City SEO agencies and one of the few Siouxland firms offering technical SEO, PPC and automation in-house. Number 8 of the digital marketing agencies in Iowa.

Who leads itRich Mackey, President.

Estimated cost

Estimated: $2,000–$6,000/mo, typical for Iowa digital marketing retainers; not a quote.

Typical industry estimate, not a quote from any firm on this list.

A fit forMedical, financial, construction and manufacturing companies that want one outside team to run websites, paid media, marketing automation and lead scoring.

Based in
Sioux City, IA
Team size
1–10 people
Led by
Rich Mackey, President
Known for
SEO and SEM · paid social · marketing automation · web design · healthcare and financial services
Best for
Medical, financial, construction and manufacturing companies that want one outside team to run websites, paid media, marketing automation and lead scoring.
Estimated cost

Estimated: $2,000–$6,000/mo, typical for Iowa digital marketing retainers; not a quote.

Typical industry estimate, not a quote from any firm on this list.

Antidote 71 homepage, captured September 28, 2026
antidote71.com · homepage on September 28, 2026

UpdateFormerly JD Gordon Creative Labs; the team now works remotely across Iowa, Nebraska, North Carolina and Australia.

Sources antidote71.com, expertise.com · LinkedIn ↗

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